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The IB kinase (IKK) complex is activated by TNF- and other cell stressors through a series of intermediate stages that result in IkB phosphorylation and ubiquitination, which in turn causes IkB degradation and activates NF-B followed by nuclear translocation to bind a specific DNA sequence (As Jr 1996

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As the solution contains 0.9% benzyl alcohol as a bacteriostatic preservative, the risk of microbial contamination in the vials is minimal